Early identification of carotid vulnerable plaque in asymptomatic patients
نویسندگان
چکیده
منابع مشابه
Vitamin D and Vulnerable Carotid Plaque.
BACKGROUND AND PURPOSE MR imaging-detected carotid intraplaque hemorrhage indicates vulnerable plaque with high stroke risk. Angiotensin II stimulates intraplaque hemorrhage in animal models, and the angiotensin system is highly regulated by vitamin D. Our purpose was to determine whether low vitamin D levels predict carotid intraplaque hemorrhage in humans. MATERIALS AND METHODS In this cros...
متن کاملAsymptomatic carotid plaque rupture with unexpected thrombosis over a non-canonical vulnerable lesion.
OBJECTIVE Several studies have demonstrated that carotid plaque rupture and thrombosis represent the most important factors correlated with the onset of acute cerebrovascular symptoms. Nevertheless, ruptured thrombotic plaques have been described also in asymptomatic patients. What still needs to be clarified is why a plaque rupture leads either to an acute ischemic syndrome or, in a minor grou...
متن کاملVulnerable plaque in a Swine model of carotid atherosclerosis.
BACKGROUND AND PURPOSE Distal embolism and acute thrombosis due to rupture of a vulnerable atherosclerotic plaque are the common mechanisms of stroke in patients with carotid disease. The purpose of this study was to develop the first animal model of vulnerable carotid atherosclerotic plaque. MATERIALS AND METHODS Carotid atherosclerotic models were created in 12 Yucatan minipigs by using a c...
متن کاملMicroembolic signals and carotid plaque characteristics in patients with asymptomatic carotid stenosis.
OBJECTIVE To investigate the association between carotid plaque characteristics and the occurrence of cerebral microemboli signals (MES) and subsequent ischemic events in patients with asymptomatic carotid stenosis (ACS). DESIGN Sixty-two asymptomatic patients with 50-99% carotid stenosis underwent transcranial Doppler (TCD) monitoring to determine the relationship between MES and plaque char...
متن کاملMRI of geometric and compositional features of vulnerable carotid plaque.
Noninvasive imaging of atherosclerotic disease provides a powerful opportunity to gain insight into the complex chain of events underlying atherogenesis, plaque progression, and ultimately those processes that result in atherothrombosis with accompanying clinical symptoms. MRI is particularly attractive because it is noninvasive and is capable of providing a rich array of information on vascula...
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ژورنال
عنوان ژورنال: BMC Cardiovascular Disorders
سال: 2020
ISSN: 1471-2261
DOI: 10.1186/s12872-020-01709-5